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Technical University of Munich

A postdoc from Prof. Matthias Hebrok’s group receives a prestigious Marie Skłodowska-Curie Postdoctoral Fellowship

We are pleased to share that Dr. Hossam Montaser, a postdoctoral researcher in Prof. Matthias Hebrok’s lab, has been awarded a Marie Skłodowska-Curie Postdoctoral Fellowship.

Hossam’s project, BetaSpReg, addresses a major challenge in diabetes research: understanding why insulin-producing beta cells progressively lose function. While beta cell transcriptional and epigenetic regulation have been widely studied, the role of alternative splicing remains largely unexplored. The project will investigate how hnRNP-family splicing regulators shape beta cell development, function, and stress resilience, and explore splice-switching oligonucleotides as a potential therapeutic strategy.

BetaSpReg aims to deliver the first mechanistic map of splicing regulation in human beta cells. In doing so, the project may open new avenues for RNA-based precision medicine in metabolic disease.

We warmly congratulate Hossam on this great achievement and look forward to the outcomes of the project.

News

MIBE & COS Seminar Series

We are happy to announce that the MIBE seminar series will be hosted at COS during the upcoming summer semester and will be dedicated to organoid research. The seminars will take place every Tuesday in the COS seminar room (3rd floor, Boltzmannstraße 12), starting on April 14 and concluding on July…

New COS building is ready: most groups have already moved in

We’re happy to share that the new COS building is ready, and most of the COS working groups have already moved in. This move marks an important milestone for COS, bringing teams together in a shared environment designed to support collaboration and day-to-day scientific exchange.

Andreas Bausch is the new Nixdorf Professor

Heinz Nixdorf Foundation supports organoid research at TUM

An all-in-one model to reconstruct the complex architecture of the liver

First author Anna Dowbaj, a newly appointed COS professor, together with a team of Prof. Meritxell Huch from MPI-CBG in Dresden, developed a novel all-in-one organoid model that is able to recapitulate the complex architecture of the liver, published in Nature.

Engineered immune cells may be able to tame inflammation

Whether it's type 1 diabetes, other autoimmune diseases or organ transplants – when the immune system gets out of balance, it can be dangerous. Instead of suppressing the entire system as a consequence and risking severe side effects, it would be preferable to regulate it in a targeted and localized…

Organoids represent the complex cell landscape of pancreatic cancer

A team led by researchers at the Technical University of Munich (TUM) has, for the first time, grown tumor organoids – three-dimensional miniature tumors in the laboratory – that mimic the different structures and characteristics of pancreatic cancer. The scientists investigated how the various…

Researching diabetes and pancreatic cancer with miniature organs

In this issue of "NewIn," we introduce Matthias Hebrok. The professor of Applied Stem Cell and Organoid Systems and director of the new TUM Center for Organoid Systems (COS) creates organ-like structures from stem cells. He uses these organoids to research pancreatic cancer, develop diagnostic…

Three ERC Advanced Grants for TUM researchers

More effective production of drugs, a way to repair human hearts, and new insights into the world of exotic particles: Research into these topics at the Technical University of Munich (TUM) will be funded with three highly endowed Advanced Grants of the European Research Council (ERC). Two further…

Global publication analysis - "Highly Cited Researchers 2023" – Five researchers from the TUM School of Life Sciences among the most cited worldwide

Five scientists from the TUM School of Life Sciences are among the most highly cited in their field. This is shown by the current publication analysis "Highly Cited Researchers 2023". A total of eleven researchers from the Technical University of Munich (TUM) were honored.

4D printing for nerve stimulation

Specific nerves may be stimulated artificially, for example to treat pain. The finer the nerves, the more difficult it is to attach the required electrodes. Researchers at the Technical University of Munich (TUM) and NTT Research have now developed flexible electrodes produced with 4D printing…

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