Guest lecture by Prof. Dr. Takahiro Muraoka, June 8, 16:00
JigSAP: Selective disassembly of supramolecular peptide hydrogels under physiological conditions

We are excited to host a guest lecture by Prof. Dr. Takahiro Muraoka (Tokyo University of Agriculture and Technology), entitled: “JigSAP: Selective disassembly of supramolecular peptide hydrogels under physiological conditions.”
Monday, June 8 | 16:00
COS Seminar Room
or online: https://teams.microsoft.com/meet/367266069458958?p=eIsCOsBG4ZDtH7ujJk
Everyone is welcome to join!
MIBE & COS Seminar Series

We are happy to conclude the first half of our MIBE & COS seminar series. Thank you all for your exceptional participation and making our seminars so lively! After a short break on May 26, see you again starting from June 2. The Seminars on Tuesday in the COS seminar room (3rd floor, Boltzmannstraße 12), or online: teams.microsoft.com/meet/381098407820354?p=v2xMieeTtkgLJDLFys until July 14.
A postdoc from Prof. Matthias Hebrok’s group receives a prestigious Marie Skłodowska-Curie Postdoctoral Fellowship

We are pleased to share that Dr. Hossam Montaser, a postdoctoral researcher in Prof. Matthias Hebrok’s lab, has been awarded a Marie Skłodowska-Curie Postdoctoral Fellowship.
Hossam’s project, BetaSpReg, addresses a major challenge in diabetes research: understanding why insulin-producing beta cells progressively lose function. While beta cell transcriptional and epigenetic regulation have been widely studied, the role of alternative splicing remains largely unexplored. The project will investigate how hnRNP-family splicing regulators shape beta cell development, function, and stress resilience, and explore splice-switching oligonucleotides as a potential therapeutic strategy.
BetaSpReg aims to deliver the first mechanistic map of splicing regulation in human beta cells. In doing so, the project may open new avenues for RNA-based precision medicine in metabolic disease.
We warmly congratulate Hossam on this great achievement and look forward to the outcomes of the project.
News
An all-in-one model to reconstruct the complex architecture of the liver
The recent study published in Nature by Anna Dowbaj together with a team of senior author Meritxell Huch (Max Planck Institute of Molecular Cell Biology and Genetics in Dresden), conducted at MPI-CBG, provides compelling evidence that integration of several critical liver cell types can be achieved to construct a functional replica of the liver. Prof. Dowbaj has recently joined the TUM and COS and will continue to expand on this groundbreaking work to establish human liver organoids that can be used for drug screening and will provide novel insights into liver function and disease. Her efforts seamlessly integrate with the existing activities at the Center focused on exploring human organoid technologies as a means to develop novel therapies.
Read more here: https://www.mpi-cbg.de/news-outreach/news-media/article/all-in-one-model-reconstructs-complex-liver-architecture